The seaport that was responsible for the tremendous wealth and expansion
of Syrian Antioch was named after Seleucus Nicator I around 300 BCE.
The port was founded first, then a trade route established, and finally
the planting of a major city. Located a few miles from the mouth of
the Orontes River, the flow of goods made their way the fifteen miles
to Antioch. There may have been about 30,000 inhabitants during the
time of Paul’s travels. Paul and Joses Barnabas sailed from Seleucia
to Cyprus on their First Mission Journey.